62nd Canadian Chemical Engineering Conference


Biotechnology

Monday AM

BIO1Plaza A

Monoclonal Antibody Bioprocess Engineering

Organizer(s) - J. Piret, A. Sen
Chair(s) - M. Butler, J. Piret

08:00 00029 Effect of Culture Conditions on the Glycosylation Pattern of mAb Aghamohseni H., *Budman H., Scharer J., Moo-Young M.
08:20 00030 Effect of Low Glucose and Glutamine Concentrations on the Glycosylation of the Camelid Monoclonal Antibody CHO EG2 *Villacrés Barragán C., $Butler M.
08:40 00031 A Kinetic Metabolic Model Describing CHO Cells Behaviour Ghorbaniaghdam A., *Jolicoeur M.
09:00 00032 Effects of Cell Culture Conditions on Lipid-Linked Oligosaccharide Intermediates of Glycosylation of a Monoclonal Antibody *Liu B., Spearman M., $Butler M.
09:20 00033 Impact of Primary Metabolism Alteration on Antibody Productivity of CHO Cell Toussaint C.
09:40 00034 Monitoring Chinese Hamster Ovary Cell Cultures using Multi-wavelength Fluorescence Spectroscopy Ohadi K., *Budman H., Legge R.L.
10:00 End of Session

BIO2Plaza B

Computational Bioengineering

Organizer(s) - J. Piret, A. Sen
Chair(s) - A. Garnier

08:00 00035 New Analytical Algorithms to Characterize Cells Kinetics and Morphology Using Phase Contrast Microscopy Juneau P.M., $Duchesne C., *Garnier A.
08:20 00036 In-Silico Design of a Novel Polymer for the Neutralization of the Anticoagulant Fondaparinux Cajiao A.C., Gopaluni B.G., *Kwok E.K., Kizhakkedathu J.N.K.
08:40 00037 Model Predictive Control of Cardiac Heart Muscle Alternantion Yapari F., *$Dubljevic S.
09:00 00038 Online Optimization with Model Discrimination of Surface Plasmon Resonance *Si Mehand M., De Crescenzo G., Srinivasan B.
09:20 00039 Ocular Drug Transport in the Posterior Segment: How Physicochemical Properties of Drugs affect their Diffusion in the Vitreous Humor Gajraj R., $Cheng Y.-L.
10:00 End of Session


Monday PM

BIO1Plaza A

Monoclonal Antibody Bioprocess Engineering

Organizer(s) - J. Piret, A. Sen
Chair(s) - M. Butler, J. Piret

Keynote Lecture:

13:00 00136 Analysis of Mab Glycosylation Pattern Through Mab Binding to Fcc Receptors. - A Surface Plasmon Resonance Biosensing Study *$Dorion-Thibaudeau J., Raymond C., De Crescenzo G., Durocher Y.
13:40 00137 Development of an In Vitro Platform for the Remodelling of Monoclonal Antibody Glycans Orr V., Ang J.C., Wagner A., Guillemette G., *Aucoin M.
14:00 00138 Modification of Monoclonal Antibody Glycans Using Glycoprotein Processing Inhibitors: Effects on Production, Activity and Stability *Spearman M.A., Okun N., Chan S., Butler M.
14:20 00139 Impact of Fc Mutations and Sialylation Method on Interactions Between Sialylated IgGs and Fc-receptors $Raymond C., Bisson L., St-Laurent G., Kelly J., *Durocher Y.
14:40 00140 Combined Metabolomic and Proteomic Analysis of Monoclonal Antibody Glycosylation under Nucleotide-Sugar Precursor Feeding Blondeel E.J., Ho R., McConkey B.J., Aucoin M.G.
15:00 Coffee Break
15:30 00141 Effect of All-Trans-Retinoic Acid on the Productivity and Glycosylation of a Heavy Chain Monoclonal Antibody Produced from Chinese Hamster Ovary Cells *Tayi V.S., Okun N.J., $Butler M.
15:50 00142 Hyper-osmolality and Autophagy Inhibition: Increased Monoclonal Antibody Production *Nasseri S.S., Braasch K., Butler M., Jardon M., Gopaluni B., $Piret J.
16:10 00143 The Changing Dielectric Properties of CHO Cells Can Be Used to Determine Early Apoptotic Events in a Bioprocess *Braasch K., Nikolic-Jaric M., $Butler M., Thomson D.J, Bridges G.E.
16:30 00144 Primary Capture of Monoclonal Antibodies with Weak Cation Exchange Membranes Hassel K.J., *Moresoli C.
16:50 00145 The Art of Enriching Glycopeptides for Downstream Mass Spectrometric Analysis Using HILIC Magnetic Beads and PABA as an Electrochemical Sensor Bodnar E., $Perreault H.
17:10 00146 Separation and Analysis of Chimeric Heavy Chain Monoclonal Antibodies by Membrane Chromatography Sadavarte R., Okun N., Speerman M., Butler M., *$Ghosh R.
17:30 End of Session

BIO3Plaza B

Biosystems Engineering

Organizer(s) - J. Piret, A. Sen
Chair(s) - A. Al Taweel

13:00 00147 Efficient Methods for Decorating and Controlling the Release of Biomolecules from Plasmonic Gold Nanostructures Pekcevik I.C., Poon L., *$Gates B.D.
13:20 00148 A Tunable Approach to Making Electrochemical Biosensors using Self-Assembly *$Gates B.D., Paul M.T.Y.
13:40 00149 Improvement of Enzyme Transport in Wood Chips for TMP Refining *Pelletier A.L., Yu Z., Xiaochun L., $Li K., Court G., Hohmann S., Snow D.
14:00 00150 Green Biocellulose Nanofibers Production using Renewable/ Sustainable Resources of Agriculture Residues Alabdallah W., *$Dahman Y.
14:20 00151 Properties and Application of Phage Ghosts Produced by Osmotic Shock and Gamma Irradiation Thompson J.W., Chen J.Z., Dubreuil M., *$Sauvageau D.
14:40 00152 Bioconversion of Natural Gas into Single Cell Protein *$Al Taweel A.M., Aufderheide B., Shah Q.
15:00 Coffee Break
15:30 00153 Effect of Microbubble Aeration on the Performance of Airlift Reactors *$Al Taweel A.M., Pallapothu S., Idhbeaa A., Ghanem A.
15:50 00154 Fluid Dynamic Gauging of Bioprocessing Biofilms on Different Substrates *Wilson D.I., $Salley B., McCormick A.J., Gordon P.W., Fisher A.C.
16:10 00155 Effective Parameters of Phenol Removal in Pure and Mixed Cultures of Alcaligenes Faecalis Manafi M., Mehrnia M., Sarrafzadeh M.
16:50 End of Session


Tuesday AM

BIO4Plaza A

Recombinant Protein Bioprocess Engineering

Organizer(s) - J. Piret, A. Sen
Chair(s) - M. Butler; J. Piret

08:00 00315 Proteomic Profiling of Antibody-Producing Chinese Hamster Ovary Cells Using 2D-DIGE and iTRAQ Technology Ho R., *Kreye S., $McConkey B.
08:20 00316 Effect of Redox Potential on Monoclonal Antibody Glycosylation in Mammalian Cell Cultures Dionne B., $Butler M.
08:40 00317 Mass Spectrometric Profiling of Glycoconjugates Pertaining to Monoclonal Antibodies Raymond C., Lattova E., *Perreault H., $Durocher Y.
09:00 00318 Plant Hydrolysates are a Viable Substitute for Animal Derived Media Components *$Murayyan A., Nowruzi K., Dutton R., Hayward G.
09:20 00319 Development of Novel Feed Additives Through the Accumulation of Recombinant Proteins in Microalgae *Potvin G., Richard A., Talbot K., $Zhang J.
09:40 00320 Optimization of Growth Rate and Hydrodynamic Studies for Cyanobacterium S. elongatus in Photobioreactor Kuan D., Posarac D., Duff S., Bi X., Yewalkar S.
10:00 End of Session


Tuesday PM

BIO5Plaza A

Cell Culture and Biomaterials

Organizer(s) - J. Piret, A. Sen
Chair(s) - A. Sen, M. Kallos

13:00 00466 Expansion of Human Synovial Fluid-Derived Mesenchymal Stem Cell Populations in Suspension Bioreactors Jorgenson K.D., Khurshid M., Hart D.A., Frank C.B., *$Sen A.
13:20 00467 Large-Scale Bioprocessing of Human Glioblastoma-Derived Tissue for High-Throughput Small-Molecule Drug Screens Panchalingam K.M., Hothi P., Shah N., Foltz G., *$Behie L.A.
13:40 00468 Morphological Evaluation and Quantification of Human Embryonic Stem Cell Cultures and the Impact of Spatial Distribution on Oxygen Transport Hunt M.M., Kallos M.S., Gates I.D.
14:00 00469 Clonal Culture of Human Embryonic Stem Cells in a Microfluidic Device for the Analysis of Population Heterogeneity *Sikorski D.J., Caron N.J., Vaninsberghe M., Hansen C.L., $Piret J.M.
14:20 00470 A Serum-free, Feeder-free Culture Medium for the Growth of Primary, Functional Human Keratinocytes Debbah I., Duchesne C., Gaillet B., Germain L., *$Garnier A.
14:40 00471 A Multi-well Flow Chamber Live Cell Imaging System to Improve Vascular Graft Biomaterials Hoesli C.A., Tremblay C., Juneau P., Boivin M., Duchesne C., Ruel J., Garnier A., *$Laroche G.
15:00 Coffee Break
15:30 00472 Preparation and Characterization of an Interconnected Porous PCL Scaffold Derived from Co-Continuous Polymer Blends *Ghavidel Mehr N., Ariganello M.B., Hoemann C.D., $Favis B.D.
15:50 00473 Effect of Peptide Secondary Structure on Adsorption and Adsorbed Film Properties to PEO Modified Surfaces Binazadeh M., *$Zeng H., Unsworth L.D.
16:10 00474 Immunomodulatory Activity of Peptide-Gold Nanoparticle Hybrids Yang H., Zhou Y., Fung S.-Y., Wu L., Waddell T.K., Perrot M., *$Liu M.
16:30 End of Session

BIO-PRegency, Balmoral

Poster Session

Organizer(s) - J. Piret, A. Sen

From 17:30 until 19:00

17:30 00475 Preparation of Multifunctional Nanoparticles for the Application in MR Imaging for Spinal Cord Injury Du Y., Tsai E., *Cao X.
17:30 00476 A Novel Wound Dressing Based on Chitosan and Aloe Vera $Mollarafie P., *Khadiv Parsi P., Zarghami R., Manafi M.
17:30 00477 Bioremediation of Recalcitrant and Polycyclic Aromatic Hydrocarbons Present in an Oil Refinery Wastewater by Three Newly Isolated Bacteria from Petroleum Sludge Pinhati F.R., *Del Aguila E.M., Conte C.A.J., Torres A.P.R., Sousa M.P., Santiago V.M.J., Silva J.T., Paschoalin V.M.F.
17:30 00478 Some Investigations on Magnetic Separation of Bovine Serum Albumin Protein using Fe3O4 Magnetite Nanoparticles - Chitosan Hydrogel Network - A Comparison Study $Sadeghi M., *Amouei Torkmahalleh M., Kazerooni H., Salehizadeh H.
17:30 00480 Novel, Modifiable Biocomposites from Biodegradable Polyurethane Reinforced with Green Biocellulose Nanofibers for Various Tissue-engineering Applications $Nakhoda H.M., *Dahman Y.
17:30 00481 Effects of Pelletization Conditions on Hardness and Dimensional Stability of Fuel Wood Pellets Lam P.Y., *$Sokhansanj S., Bi X.T., Lim C.J., Lau A.K., Lam P.S.
17:30 00482 Antimicrobial Studies on Polyurethane Coatings *Azhie K., Lotus A.F., $Charpentier P.A.
17:30 00483 Influence of the Extraction Temperature and Extraction Time on the Composition of Mint Essential Oil Using Microwave Extraction *Costa S.S., Gariepy Y., Rocha S.C.S., Raghavan G.S.V.
17:30 00484 Novel Plethysmography System for the Analyzing and Prediction of Radiation-induced Lung Injury *$Coates J.T., El Naqa I.
17:30 00590 Intrinsic Fluorescence Spectroscopy and Antioxidant Capacity of Soy Protein Hydrolysates Produced by Sequential Membrane Ultrafiltration and Nanofiltration Ranamukhaarachchi S., Peiris R.H., *Moresoli C.

Wednesday AM

BIO6Plaza A

Separation and Downstream Processing

Organizer(s) - J. Piret, A. Sen
Chair(s) - A. Sen

09:00 00586 The Use of CO2 for Reversible pH Shifting and Organic Acid Recovery in Polymer-loaded Two-phase Partitioning Bioreactors Peterson E.C., $Daugulis A.J.
09:20 00587 Trends and Challenges in Large-Scale Enzymatic Phenol Removal Process *$Nazari K., Haghighian Z., Fateminasab F., Moosavi-Movahedi A.A.
09:40 00588 Improving Bio-Butanol Production by Adsorption: Equilibrium and Kinetic Studies for Adsorbent Screening Abdehagh N., *Tezel F.H., Thibault J.
10:00 End of Session


Wednesday PM

BIO7Plaza A

Biorefining and Biofuels

Organizer(s) - J. Piret, A. Sen
Chair(s) - H. Trajano

13:00 00676 Growth of Microalgae for Concurrent Objectives of Biodiesel Production and Wastewater Treatment *$Al-Zuhair S., Taher H., Al-Marzouqi A., Hayek Y.
13:20 00677 Process Simulation and Economic Evaluation for Bioethanol Production Implementing the Enzyme Recycling by Re-adsorption Rosales Calderon O.
13:40 00678 Butanol Recovery from ABE Fermentation Broth by a Two-step Adsorptive Separation with SAPO-34 Zeolite and ZIF-8 MOF Cousin Saint Remi J., Remy T., *Baron G.V., $Denayer J.F.M.
14:00 00679 Simulation of Ethanol Extractive Distillation with Mixed Glycols as Separating Agent *Gil I.D., Rodríguez G., García L.C.
14:20 00479 Ethanol Dehydration with Protein Extracted Canola Meal in a Pressure Swing Adsorption Process Ranjbar Z., Dalai A.K., *Niu C.H.
14:40 00680 Peroxidases as Valuable Biocatalysts in Biochemical Technology Nazari M., *$Nazari K.
15:00 Coffee Break
15:30 00682 Characterization of Cell Wall Structure on the Removal of Hemicellulose from Populus during Flowthrough Pretreatment *Trajano H.L., Pattathil S., Tomkins B.A., Tschaplinski T.J., Van Berkel G.J., Hahn M.G., $Wyman C.E.
15:50 00683 Delignification of Wheat Straw with Ozone, its Kinetics and Selectivity *Shahzad Baig K., $Turcotte G., Doan H.
16:10 00684 Evaluation of Propionibacterium freudenreichii Strains as Biocatalysts in a Glycerol Oxidizing Microbial Fuel Cell Sivell J., Reiche A.E., $Kirkwood K.M.
16:30 00685 Enhancing Biosludge Dewaterability Using Biomolecules: The Case of Lysozyme *Bonilla I.S., Yakunin A.F., $Allen D.G.
16:50 00686 The Mutual Interdependency of Pretreatment and Enzymatic Hydrolysis to Ensure the Effective Production of a Competitive Sugar Stream from Biomass Substrates *Arantes V., $Saddler J.N.
17:10 00681 Enhanced Green Production of Future Biofuel, Biobutanol, through Novel Fusants of Tri- Mohtasebi B., Dahman Y.
17:30 End of Session


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Bold text denotes the presenting author.   If present, * denotes the corresponding author and $ denotes the principal investigator.

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